The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency
Luis Gruberg, MD*,
Gary S. Mintz, MD*,
Roxana Mehran, MD ,
George Dangas, MD, PhD,
Alexandra J. Lansky, MD,
Kenneth M. Kent, MD, PhD*,
Augusto D. Pichard, MD*,
Lowell F. Satler, MD* and
Martin B. Leon, MD
* Cardiac Catheterization Laboratory, Washington Hospital Center, Washington, DC, USA
Cardiovascular Research Foundation, New York, New York, USA
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Figure 1 A flow diagram detailing the mortality of 439 patients with pre-existing renal insufficiency undergoing percutaneous coronary intervention.
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Figure 2 Kaplan-Meier estimates of survival for group 1 (renal function deterioration, solid line) versus group 2 (no increase in serum creatinine, dashed line, p < 0.001).
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Figure 3 Relation of the percentage increase in serum creatinine to 1-year mortality. There was a significant increase in mortality when the increase in creatinine was greater than 25% (p < 0.0001).
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Figure 4 Kaplan-Meier estimates of survival comparing diabetic patients versus patients who were not diabetic in group 1 (renal function deterioration, p = NS) and diabetic patients versus patients who were not diabetic in group 2 (no increase in serum creatine, p = NS). DM = diabetes mellitus.
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