This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Goodman, S. G. Search for Related Content PubMed PubMed Citation Articles by Goodman, S. G.

Low molecular weight heparin decreases rebound ischemia in unstable angina or non-Q-wave myocardial infarction: the Canadian ESSENCE ST segment monitoring substudy

Shaun G. Goodman, MD, FACC^*, Aiala Barr, PhD^*, Anatoli Sobtchouk, MD^*, Marc Cohen, MD, FACC, Gregg J. Fromell, MD, Luc Laperrière, MD, Carol Hill, RN^*, Anatoly Langer, MD, FACC^* for the Canadian Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events (ESSENCE) ST Segment Monitoring Substudy Group

^* Canadian Heart Research Center, Division of Cardiology, St. Michael’s Hospital, University of Toronto, Toronto, Canada
Division of Cardiology, Hahnemann University Hospital, Philadelphia, Pennsylvania, USA
Covance Clinical Trials Research and Development, Inc., Princeton, New Jersey, USA
Fournier Pharma and Department of General Medicine, Hospital Center of the University of Montreal, Montreal, Quebec, Canada

View larger version (28K): [in a new window]   Figure 1 Flowchart showing disposition of patients.

View larger version (16K): [in a new window]   Figure 2 Kaplan-Meier plot of 1-year event-free survival from death or nonfatal myocardial (re)infarction among patients with (solid line, n = 87) and without (dashed line, n = 144) ST segment change (ischemia) during either initial or study drug discontinuation monitoring.

View larger version (23K): [in a new window]   Figure 3 Kaplan-Meier plot of 1-year event-free survival from death or nonfatal myocardial (re)infarction among heparin patients (solid lines): 1) with ST segment change (ischemia) during continuous monitoring (heavy solid line, n = 52) and 2) without ischemia during continuous monitoring (light solid line, n = 67) and among enoxaparin patients (dashed lines): 1) with ischemia (heavy dashed line, n = 35) and 2) without ischemia (light dashed line, n = 77).

View larger version (23K): [in a new window]   Figure 4 Kaplan-Meier plot of 1-year event-free survival from death or nonfatal myocardial (re)infarction among patients with ST segment shift on baseline 12-lead ECG (solid lines): 1) with ST segment change (ischemia) during continuous monitoring (heavy solid line, n = 44) and 2) without ischemia during continuous monitoring (light solid line, n = 41) and among patients without ST segment shift on baseline 12-lead ECG (dashed lines): 1) with ischemia (heavy dashed line, n = 43) and 2) without ischemia (light dashed line, n = 103).