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A common variant of the AMPD1 gene predicts improved cardiovascular survival in patients with coronary artery disease

^a University of Utah, LDS Hospital, Salt Lake City, Utah, USA

View larger version (14K): [in a new window]   Figure 1 Kaplan-Meier survival-time plot for cardiovascular death by AMPD1 genotype (wild type vs. variant heterozygote or homozygote). There are four events (4.4%) among 90 patients carrying the mutant polymorphism and 33 events (11.9%) among noncarriers, a statistically significant difference (log-rank statistic 4.0, p = 0.046; Breslow statistic 4.1, p = 0.043). Solid line = AMPD1(–) variant carrier; dotted line = variant noncarrier.