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How deadly is the "deadly quartet"?

A post-CABG evaluation

^* Section of Preventive Cardiology, Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA

View larger version (25K): [in a new window]   Figure 1 Raw incidence of mortality overall and by gender. Open bars = overall risk factors; hatched bars = male risk factors; solid bars = female risk factors.

View larger version (29K): [in a new window]   Figure 2 Expected (line) and observed (bars) prevalence of patients with zero, one, two, three or four of the deadly quartet risk factors (hypertension, diabetes, hypertriglyceridemia, obesity). Open bars = overall risk factors; hatched bars = male risk factors; solid bars = female risk factors.

View larger version (15K): [in a new window]   Figure 3 Kaplan-Meier survival curves showing the estimated risk of all-cause mortality for men with 0, 1, 2, 3 and 4 of the deadly quartet risk factors (obesity, diabetes, hypertension and hypertriglyceridemia).

View larger version (16K): [in a new window]   Figure 4 Kaplan-Meier survival curves showing the estimated risk of all-cause mortality for women with 0, 1, 2, 3 and 4 of the deadly quartet risk factors (obesity, diabetes, hypertension and hypertriglyceridemia).