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Improving outcome over time of percutaneous coronary interventions in unstable angina

Mandeep Singh, MD^*, Charanjit S. Rihal, MD, FACC^*, Peter B. Berger, MD, FACC^*, Malcolm R. Bell, MB, BS^*, Diane E. Grill, MS, Kirk N. Garratt, MD, FACC^*, Gregory W. Barseness, MD, FACC^* and David R. Holmes, Jr., MD, FACC^*

^* Division of Internal Medicine and Cardiovascular DiseasesRochester, Minnesota, USA.
Section of Biostatistics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA

View larger version (10K): [in a new window]   Figure 1 Estimated survival curves for mortality for each of the time periods based on the Cox proportional hazard model. Risk of 1994 to 1998 relative to 1979 to 1989 is 0.67, p < 0.001. Risk of 1990 to 1993 relative to 1979 to 1989 is 0.87, p = 0.08.

View larger version (11K): [in a new window]   Figure 2 Estimated event-free survival curves for death and myocardial infarction (MI): 1994 to 1998 relative to 1979 to 1989 is 0.82, p = 0.02. Risk of 1990 to 1993 relative to 1979 to 1989 is 0.96, p = 0.53.

View larger version (13K): [in a new window]   Figure 3 Estimated event-free survival curves for death, myocardial infarction (MI), coronary artery bypass surgery or repeat revascularization (revasc): 1994 to 1998 relative to 1979 to 1989 is 0.85, p = 0.002. Risk of 1990 to 1993 relative to 1979 to 1989 is 1.07, p = 0.14.