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High dose angiotensin-converting enzyme inhibition prevents fluid volume expansion in heart transplant recipients

Randy W. Braith, PhD^*, Roger M. Mills, MD, FACC, Christopher S. Wilcox, MD, PhD^||, Matthew J. Mitchell, MS^*, James A. Hill, MD, FACC and Charles E. Wood, PhD

^* Center for Exercise Science, College of Health and Human Performance, University of Florida, Gainesville, Florida, USA
Department of Medicine, University of Florida, Gainesville, Florida, USA
Department of Physiology University of Florida, Gainesville, Florida, USA
Cleveland Clinic, Cleveland, Ohio, USA
^|| Department of Medicine, Georgetown University, Washington, DC, USA

View larger version (19K): [in a new window]   Figure 1 Plasma volume values in age-matched normal control subjects (n = 7) in the same cohort of HTRs (n = 8) before and after stabilization on captopril (225 mg/day) and in age-matched liver transplant recipients (n = 6). Data are presented as the mean value ± SEM. *p < 0.05 versus HTR after captopril, control and liver transplant groups.