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Prevalence and correlates of aortic regurgitation in american indians: the Strong Heart Study

Nathaniel E. Lebowitz, MD^a, Jonathan N. Bella, MD^a, Mary J. Roman, MD, FACC^a, Jennifer E. Liu, MD^a, Dawn P. Fishman, BA^a, Mary Paranicas, BA^a, Elisa T. Lee, PhD^*, Richard R. Fabsitz, MA, MPH, Thomas K. Welty, MD, Barbara V. Howard, PhD and Richard B. Devereux, MD, FACC^a

^a Department of Medicine, The New York Hospital–Cornell Medical Center, New York, New York, USA
^* School of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
National Heart Lung and Blood Institute, Bethesda, Maryland, USA
Aberdeen Area Tribal Chairman’s Health Board, Rapid City, South Dakota, USA
Medlantic Research Institute, Washington, DC, USA

View larger version (13K): [in a new window]   Figure 1 The prevalences of both mild (1+) AR (solid bars) and more severe (2+) AR (open bars) in Strong Heart Study participants show strong positive correlations to increasing age (p < 0.001).

View larger version (16K): [in a new window]   Figure 2 The prevalences of both mild (1+) AR (solid bars) and more severe (2+) AR (open bars) show progressive increases from individuals with no AS to those with mild AS to those with moderate or severe AS (p < 0.001).

View larger version (13K): [in a new window]   Figure 3 The prevalences of both mild (1+) AR (solid bars) and more severe (2+) AR (open bars) were substantially higher (p < 0.001) in individuals with bicuspid as opposed to trileaflet aortic valves.

View larger version (14K): [in a new window]   Figure 4 The prevalences of both mild (1+) AR (solid bars) and more severe (2+) AR (open bars) were higher (p < 0.01) in individuals with thickened aortic valve cusps versus cusps of normal thickness.