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J Am Coll Cardiol, 2000; 36:410-416
© 2000 by the American College of Cardiology Foundation
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Atorvastatin but not L-arginine improves endothelial function in type I diabetes mellitus: a double-blind study

Michael J. Mullen, MRCP*, David Wright, PhD{dagger}, Ann E. Donald, AVT*, Sara Thorne, MD, MRCP*, Hyeyoung Thomson, BSc* and John E. Deanfield, FRCP*

* Vascular Physiology Unit, Great Ormond Street Hospital for Children, London, UK
{dagger} Department of Statistical Science, University College London, Gower Street, London, UK



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Figure 1 Study protocol. Subjects were randomized to either placebo, L-arginine (7 g twice daily), atorvastatin (40 mg/day) or combination therapy. Vascular function was assessed noninvasively at baseline and after six weeks of treatment.

 




 
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