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Long-term outcome in congenitally corrected transposition of the great arteries

A multi-institutional study

Thomas P. Graham, Jr., MD, FACC^*, Yvonne D. Bernard, RN^*, Beverly G. Mellen, PhD^*, David Celermajer, MD, Helmut Baumgartner, MD, Frank Cetta, MD, FACC, Heidi M. Connolly, MD, FACC^||, William R. Davidson, MD, FACC^¶, Mikael Dellborg, MD^#, Elyse Foster, MD, FACC^**, Welton M. Gersony, MD, FACC, Ira H. Gessner, MD, FACC, Roger A. Hurwitz, MD, FACC, Harald Kaemmerer, MD^||, John D. Kugler, MD, FACC^¶¶, Daniel J. Murphy, MD, FACC^##, Jacqueline A. Noonan, MD, FACC^***, Cynthia Morris, MD, Joseph K. Perloff, MD, FACC, Stephen P. Sanders, MD, FACC and James L. Sutherland, MD, FACC^||||

^* Vanderbilt University Medical Center, Nashville, Tennessee, USA
Royal Prince Alfred Hospital, Sydney, Australia
Vienna General Hospital, Vienna, Austria
Loyola University, Chicago, Illinois, USA
^|| Mayo Clinic, Rochester, Minnesota, USA
^¶ Hershey Medical Center, Hershey, Pennsylvania, USA
^# Sahlgrenska University/Ostra Hospital, Goteborg, Sweden
^** University of California, San Francisco, California, USA
Babies Hospital, New York, New York, USA
University of Florida, Gainesville, Florida, USA
Indiana University, Indianapolis, Indiana, USA
^|| Hannover Medical School, Hannover, Germany
^¶¶ University of Nebraska, Omaha, Nebraska, USA
^## Cleveland Clinic, Cleveland, Ohio, USA
^*** University of Kentucky, Lexington, Kentucky, USA
University of Oregon, Portland, Oregon, USA
University of California, Los Angeles, California, USA
Duke University, Durham, North Carolina, USA
^|||| Children’s Heart Center, Atlanta, Georgia, USA

View larger version (14K): [in a new window]   Figure 1 Probability of freedom from CHF for group I (associated lesions) and group II (no significant associated lesions) as a function of increasing age (N = 175 instead of 182 because it was unclear in 7 patients whether they had clinical CHF).

View larger version (14K): [in a new window]   Figure 2 Probability of freedom from moderate or severe RV dysfunction as a function of increasing age. (N = 168 because data were unavailable to make this determination in 14 patients.)

View larger version (13K): [in a new window]   Figure 3 Probability of freedom from mild, moderate, or severe left ventricular dysfunction with increasing age (N = 147 because data were unavailable to make this determination in 35 patients).

View larger version (16K): [in a new window]   Figure 4 Warnes-Somerville functional classification for both patient groups.

View larger version (14K): [in a new window]   Figure 5 Toronto functional classification for both patient groups.