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Coronary microembolization

Raimund Erbel, MD, FESC, FACC^* and Gerd Heusch, MD, FESC, FACC

^* Departments of Cardiology, University of Essen Medical School, Essen, Germany
Pathophysiology, University of Essen Medical School, Essen, Germany

View larger version (180K): [in a new window]   Figure 1 Experimental microinfarct with inflammatory response in a myocardial area perfused by a small artery that has been embolized with microspheres of 42 µm in diameter. Calibration 50 µm.

View larger version (19K): [in a new window]   Figure 2 Schematic presentation of epicardial plaque fissuring/plaque rupture/thrombosis inducing embolization of atherosclerotic and thrombotic material into the microcirculation, resulting in arrhythmias, micronecrosis, contractile dysfunction and reduced coronary reserve (modified from reference 41).