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A comparison of systematic stenting and conventional balloon angioplasty during primary percutaneous transluminal coronary angioplasty for acute myocardial infarction

Luc Maillard, MD, PhD^a, Martial Hamon, MD^*, Khalife Khalife, MD, Philippe Gabriel Steg, MD, FACC, Farzin Beygui, MD, Jean-Leon Guermonprez, MD^||, Christian M. Spaulding, MD^¶, Jean-Marc Boulenc, MD^#, Janusz Lipiecki, MD^**, Antoine Lafont, MD, PhD, Philippe Brunel, MD, Gilles Grollier, MD, Rene Koning, MD^||||, Pierre Coste, MD^¶¶, Xavier Favereau, MD^##, Bernard Lancelin, MD^***, Eric Van Belle, MD, PhD, Patrick Serruys, MD, PhD, FACC, Jean-Pierre Monassier, MD^*, Philippe Raynaud, MD^a for the STENTIM-2 Investigators

^a CHU Tours, Tours, France
^* CH Mulhouse, Mulhouse, France
CH Metz, Metz, France
CHU Bichat, Paris, France
CHU Necker, Paris, France
^|| CHU Broussais, Paris, France
^¶ CHU Cochin, Paris, France
^# Clinique St. Joseph, Colmar, France
^** CHU Clermont-Ferrand, Clermont-Ferrand, France
CHU Boucicaut, Paris, France
CHU Nantes, Nantes, France
CHU Caen, Caen, France
^|||| CHU Rouen, Rouen, France
^¶¶ CHU Bordeaux, Bordeaux, France
^## CMC Parly 2, Le Chesnay, France
^*** CC Marie Lannelongue, Le Plessis Robinson, France
CHU Lille, Lille, France
University Hospital Rotterdam Dijkzigt, Thorax Center, Rotterdam, The Netherlands

View larger version (37K): [in a new window]   Figure 1 Trial flow chart. pts = patients.

View larger version (17K): [in a new window]   Figure 2 Cumulative frequency distribution curves for the two groups for minimal lumen diameter (MLD) at baseline, after the procedure and at six-month follow-up. There was no difference at baseline between the groups. After the procedure and at follow-up, minimal lumen diameter was larger in the stent group (solid line) than in the balloon angioplasty group (dashed line).

View larger version (14K): [in a new window]   Figure 3 Kaplan-Meier survival curves for major adverse cardiac events (MACE). At one year, 80.2% of the patients in the stent group (solid line) were event free. Dashed line = balloon angioplasty group.

View larger version (15K): [in a new window]   Figure 4 Kaplan-Meier curves for second revascularization. There were less patients in the stent group (solid line) than in the balloon angioplasty group (dashed line) requiring a second revascularization procedure.