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Corrected coronary flow velocity reserve: a new concept for assessing coronary perfusion

Heinrich Wieneke, MD^*, Michael Haude, MD^*, Junbo Ge, MD, FACC, Christoph Altmann, MD^*, Sigrid Kaiser, MS, Dietrich Baumgart, MD^*, Clemens von Birgelen, MD, PhD^*, Dirk Welge, MD^* and Raimund Erbel, MD, FACC^*

^* Department of Cardiology, University Hospital Essen, Center of Internal Medicine, Essen, Germany
Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Shanghai, China
Institute for Medical Informatics, Biometry and Epidemiology, University Clinics of Essen, Essen, Germany

View larger version (26K): [in a new window]   Figure 1 Univariate regression analysis between systolic pressure, diastolic pressure, heart rate, age, baseline average peak velocity (bAPV), hyperemic average peak velocity (hAPV), body mass index (BMI) and coronary flow velocity reserve (CFVR). Values are plotted against log10-transformed CFVR values. Results are shown for the left anterior descending artery (LAD).

View larger version (16K): [in a new window]   Figure 2 Comparison of standard deviation as a measure of variability of coronary flow velocity reserve (CFVR) and corrected coronary flow velocity reserve (CFVRcorr). The figure indicates that the standard deviation of the new parameter ‘CFVRcorr’ is significantly lower than the standard deviation of traditional CFVR. LAD = left anterior descending; LCX = left circumflex artery; RCA = right coronary artery.