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Attenuated coronary flow reserve and vascular remodeling in patients with hypertension and left ventricular hypertrophy

^a Center for Coronary Physiology and Imaging, Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA

View larger version (16K): [in a new window]   Figure 1 Mean (±SE) vessel area, lumen area and plaque area in the three study groups. *p < 0.01 for the comparison with group 3; 2. HTN = hypertension; LVH = left ventricular hypertrophy.

View larger version (12K): [in a new window]   Figure 2 The relationship between baseline coronary blood flow (CBF) (ml/min) and left ventricular mass (LVM) index (g/m2).

View larger version (18K): [in a new window]   Figure 3 Coronary flow reserve (CFR) in response to adenosine among the study groups. There was significant impairment of CFR in patients with hypertension and left ventricular hypertrophy (LVH) compared with that of the other groups (p < 0.05).