Regional myocardial blood flow in patients with sick sinus syndrome randomized to long-term single chamber atrial or dual chamber pacingeffect of pacing mode and rate
Jens Cosedis Nielsen, MDa,
Morten Bøttcher, MDa,
Torsten Toftegaard Nielsen, MD, DMSca,
Anders Kirstein Pedersen, MD, DMSca and
Henning Rud Andersen, MD, DMSca
a Department of Cardiology B, Skejby Sygehus, Aarhus University Hospital, Brendstrupgaardsvej, 8200-DK, Aarhus N, Denmark

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Figure 1 Time line diagram of measurements in this study. Positron emission tomography scanning and echocardiography at follow-up were done within two months of each other in each patient. AAI = single chamber atrial pacing; DDD = dual chamber pacing; PET = positron emission tomography.
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Figure 2 Individual global mean MBF in the single chamber atrial (AAI) and dual chamber (DDD) groups at pacing rate 60 beats/min (MBF-60) and 90 beats/min (MBF-90) and in the DDD group also during temporary pacing in the AAI mode, 60 beats/min (MBF [DDD AAI]-60). For statistical comparisons see text and Table 2. MBF = myocardial blood flow.
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Figure 3 Individual MBF in each of the four regions in the dual chamber (DDD) group measured at pacing rate 60 beats/min (MBF-60) and 90 beats/min (MBF-90) and during temporary pacing in the AAI mode, 60 beats/min (MBF [DDD AAI]-60). LAD, LCX and RCA indicate the three major coronary vascular territories. For statistical comparisons see text and Table 2. AAI = single chamber atrial pacing; LAD = left anterior descending artery; LCX = left circumflex artery; MBF = myocardial blood flow; RCA = right coronary artery.
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