American College of Cardiology/ European Society of Cardiology international study of angiographic data compression phase III
Measurement of image quality differences at varying levels of data compression
R.üdiger Brennecke, PhD*,
Udo Bürgel, MS*,
R.üdiger Simon, MD, FACC ,
Gerd Rippin, MS ,
Hans Peter Fritsch, MS*,
Tim Becker, MS and
Steven E. Nissen, MD, FACC
* II Medical Clinic, Johannes-Gutenberg-University Mainz, Germany
Medical Clinic, Albrechts-University Kiel, Germany
Department of Medical Statistics, Johannes-Gutenberg-University Mainz, Germany
Cleveland Clinic Foundation, Cleveland, Ohio, USA

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Figure 1 Allocation (percent of evaluations) of diagnostic quality scores (QD1, QD2; for score definition see Table 3) for DC+ (display controls enabled) and for DC raters (display controls disabled).
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Figure 2 Allocation (percent of evaluations) of diagnostic quality scores (QD1, QD2; for score definition see Table 3) for GQ+ images (acceptable general image quality) and for GQ images (general image quality not acceptable).
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Figure 3 Allocation (percent of evaluations) of quality scores QA and QD in relation to compression ratios, DC rater group (13 raters). The scores and the gray scale patterns used for the quality scores are defined in Table 3.
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Figure 4 Allocation (percent of evaluations) of quality scores QA and QD in relation to compression ratios, DC+ rater group (6 raters). The scores and the gray scale patterns used for the quality scores are defined in Table 3.
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Figure 5 Plot demonstrating the significance (p-value) of Student t-test for equivalence as a function of the tolerance limit delta for the total diagnostic error in the DC+ and the DC rater groups at CR 10:1 and CR 16:1. Solid diamond = DC+ for CR 10:1; solid square = DC+ for CR 16:1; solid triangle = DC for CR 10:1; x DC for CR 16:1. The intercepts between these functions and the horizontal reference line (p = 0.05) define the delta that has to be accepted if one wants to consider the error distributions at baseline (CR 1:1) and at CR 10:1 or CR 16:1 as equal with p = 0.05. For results compare Table 9.
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