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Clinical significance of increased plasma concentration of macrophage colony–stimulating factor in patients with angina pectoris

^a First Department of Internal Medicine, Nippon Medical School, Tokyo, Japan

View larger version (10K): [in a new window]   Figure 1 Circulating MCSF concentrations in patients with UA, patients with SA and control subjects. ***p < 0.001 (by post hoc analysis).

View larger version (21K): [in a new window]   Figure 2 Changes in the circulating MCSF concentration in patients with CAD and in control subjects. The plasma MCSF concentration increased in proportion to the number of diseased coronary arteries, giving a significant positive correlation between the MCSF concentration and the number of diseased coronary arteries (r = 0.328, p < 0.001). Co = control subjects.

View larger version (16K): [in a new window]   Figure 3 Cumulative two-year cardiac event-free survival curves for patients with angina pectoris. The cardiac event-free rate in patients with an MCSF concentration 950 pg/ml is significantly lower than that in patients with an MCSF concentration <950 pg/ml (p < 0.001).