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Importance of imaging method over imaging modality in noninvasive determination of left ventricular volumes and ejection fraction

Assessment by two- and three-dimensional echocardiography and magnetic resonance imaging

Michael L. Chuang, MS^*, Mark G. Hibberd, MD, PhD^*, Carol J. Salton, BA^*, Raymond A. Beaudin, MS, Marilyn F. Riley, BS^*, Robert A. Parker, ScD, Pamela S. Douglas, MD, FACC^* and Warren J. Manning, MD, FACC^*

^* Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Hewlett Packard Company, Andover, Massachusetts, USA
Biometrics Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA

View larger version (33K): [in a new window]   Figure 1 Limits of agreement for LVEF between volumetric MRI (Vol MRI) biplane MRI (Bi MRI) volumetric (3D) echocardiography (Vol Echo) and biplane echocardiography (Bi Echo). In each graph the central horizontal line indicates the mean bias or systematic difference; upper and lower lines represent 95% confidence intervals.

View larger version (30K): [in a new window]   Figure 2 Comparisons of individual EF measures between imaging methods. Open diamonds indicate patients whose classification by LVEF changed between imaging methods: (a) Volumetric MRI (Vol MRI) versus volumetric echocardiography (Vol Echo); (b) volumetric MRI versus biplane MRI (Bi MRI); (c) biplane MRI versus biplane echocardiography (Bi Echo). The numbers of patients whose functional classification changed between imaging methods are tabulated in Table 2.