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Serum amyloid A predicts early mortality in acute coronary syndromes: a TIMI 11A substudy

David A. Morrow, MD^*, Nader Rifai, PhD, Elliott M. Antman, MD, FACC^*, Debra L. Weiner, MD, PhD, Carolyn H. McCabe, BS^*, Christopher P. Cannon, MD, FACC^* and Eugene Braunwald, MD, FACC^*

^* Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA
Department of Laboratory Medicine, Children’s Hospital, Boston, Massachusetts, USA

View larger version (15K): [in a new window]   Figure 1 Mortality at 14 days by SAA concentration in all patients and those with negative (neg) rapid cTnT assays. SAA = serum amyloid A. SAA concentrations: open square = quintiles 1–4; closed square = quintile 5.

View larger version (13K): [in a new window]   Figure 2 Risk stratification by SAA and rapid assay status expressed as 14-day mortality by SAA and rapid cTnT result. Early positive rapid assays could be read positive by 10 minutes. cTnT = cardiac specific troponin T; Neg = negative; Pos = positive; Q = quintile; SAA = serum amyloid A.