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J Am Coll Cardiol, 2000; 35:29-35
© 2000 by the American College of Cardiology Foundation
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Lack of association between polymorphisms of eight candidate genes and idiopathic dilated cardiomyopathy

The CARDIGENE study

Laurence Tiret, PhD*, Christine Mallet, MSc{dagger}, Odette Poirier, PhD*, Viviane Nicaud, MA*, Alain Millaire, MD, PhD{ddagger}, Jean-Brieuc Bouhour, MD§, G.érard Roizès, PhD||, Michel Desnos, MD, Richard Dorent, MD#, Ketty Schwartz, PhD{dagger}{dagger}, François Cambien, MD*, Michel Komajda, MD** for the CARDIGENE Group

* INSERM U525, Paris, France
{dagger} INSERM SC7, Paris, France
{ddagger} CHR de Lille, Lille, France
§ CHR de Nantes, Nantes, France
|| INSERM U249, Montpellier, France
Hôpital Boucicaut, Paris, France
# Service de Chirurgie Cardiaque, Groupe Hospitalier Pitié-Salpêtrière, Paris, France
** Service de Cardiologie, Groupe Hospitalier Pitié-Salpêtrière, Paris, France
{dagger}{dagger} INSERM U523, Paris, France



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Figure 1 Genotypic odds ratios for DCM and 95% confidence intervals, assuming a recessive (left) or dominant (right) genetic model. For all polymorphisms, the major allele was taken as the reference allele, except for ACE I/D where I was the reference allele. For TGFB1 R25P and BNP C-1563T, the recessive model was not considered because of the low frequency of the minor allele.

 





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