Morphology of vulnerable coronary plaque: insights from follow-up of patients examined by intravascular ultrasound before an acute coronary syndrome
Masakazu Yamagishi, MD, FACCa,
Mitsuyasu Terashima, MD*,
Kojiro Awano, MD*,
Mikihiro Kijima, MD ,
Satoshi Nakatani, MD, FACCa,
Satoshi Daikoku, MDa,
Kenichi Ito, MDa,
Yoshio Yasumura, MDa and
Kunio Miyatake, MD, FACCa
a Cardiology Division of Medicine, National Cardiovascular Center, Suita, Japan
* Division of Cardiology, Miki City Hospital, Miki, Japan
Division of Cardiology, Hoshi General Hospital, Koriyama, Japan

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Figure 1 Representative intravascular ultrasound image of vulnerable atherosclerotic plaque. (Left) The right coronary angiography showed multiple luminal irregularities. (Right) (A) At the distal portion, there existed mild concentric lesion. (B) In the proximal portion there was a significant eccentric lesion in which the echolucent area with percent plaque area of 67% was seen (arrow). (C) At the very proximal of this artery, there was also eccentric lesion with relatively high echo density. All three lesions were examined at follow-up.
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Figure 2 Coronary angiography before and after emergent angioplasty. Three months after registration, the patient had acute inferior myocardial infarction. Under these conditions (A) the coronary artery was totally occluded at the portion where the eccentric plaque with echolucent area had been seen by ultrasound. (B) Emergent balloon angioplasty that was done at the site of total occlusion resulted in complete recanalization of this artery.
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