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Sudden death in mitral regurgitation due to flail leaflet

Francesco Grigioni, MD^*, Maurice Enriquez-Sarano, MD, FACC^*, Lieng H. Ling, MD^*, Kent R. Bailey, PhD, James B. Seward, MD, FACC^*, A. Jamil Tajik, MD, FACC^* and Robert L. Frye, MD, FACC^*

^* Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
Section of Biostatistics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA

View larger version (15K): [in a new window]   Figure 1 Incidence of total mortality, cardiac mortality and sudden death in patients with MR-FL. The event rates ± SEE at 10 years are indicated.

View larger version (32K): [in a new window]   Figure 2 Relation between New York Heart Association (NYHA) functional class at baseline and sudden death. Left, Yearly rates of sudden death (±SEE) according to functional classes I, II and III or IV. Right, Number of sudden death events according to functional classes I, II and III or IV.

View larger version (30K): [in a new window]   Figure 3 Relation between left ventricular ejection fraction (LVEF) at baseline and sudden death. Left, Yearly rates of sudden death (±SEE) according to LVEF classified as 60%, 50% to 59% and <50%. Right, Number of sudden death events according to LVEF classified as 60%, 50% to 59% and <50%.

View larger version (34K): [in a new window]   Figure 4 Relation between cardiac rhythm (sinus rhythm or atrial fibrillation) at baseline and sudden death. Left, Yearly rates of sudden death (±SEE) in patients in sinus rhythm and atrial fibrillation. Right, Number of sudden death events observed in patients in sinus rhythm and atrial fibrillation.