This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Wiedermann, C. J. Articles by Willeit, J. Search for Related Content PubMed PubMed Citation Articles by Wiedermann, C. J. Articles by Willeit, J.

Association of endotoxemia with carotid atherosclerosis and cardiovascular disease

Prospective results from the bruneck study

Christian J. Wiedermann, MD^*, Stefan Kiechl, MD, Stefan Dunzendorfer, MD^*, Peter Schratzberger, MD^*, Georg Egger, MD, Friedrich Oberhollenzer, MD and Johann Willeit, MD

^* Department of Internal Medicine, Medical Faculty, University of Innsbruck, Innsbruck, Austria
Department of Neurology, Medical Faculty, University of Innsbruck, Innsbruck, Austria
Department of Internal Medicine, Federal Hospital, Bruneck, Italy

View larger version (14K): [in a new window]   Figure 1 Frequency distribution of endotoxin levels (pg/ml) (n = 516).

View larger version (30K): [in a new window]   Figure 2 Binary-type association between endotoxin plasma level and atherosclerosis risk. OR = odds ratio; AS = atherosclerosis.

View larger version (51K): [in a new window]   Figure 3 Risk of incident carotid atherosclerosis associated with endotoxin levels >50 pg/ml in nonsmokers, ex-smokers, and current smokers. **p < 0.01 for effect modification; OR = odds ratio; AS = atherosclerosis.

View larger version (43K): [in a new window]   Figure 4 Age- and gender-adjusted incidence of carotid atherosclerosis according to endotoxin level and smoking status. AS = atherosclerosis. **p < 0.01; n.s. = not significant (vs. nonsmokers with endotoxin 50 pg/ml).

View larger version (47K): [in a new window]   Figure 5 Risk of incident carotid atherosclerosis associated with endotoxin levels >50 pg/ml according to smoking status and presence of infectious diseases. The p values were derived from multivariate logistic regression analysis (*p < 0.05; **p < 0.01). OR = odds ratio; AS = atherosclerosis.