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Circadian variation of malignant ventricular arrhythmias in patients with ischemic and nonischemic heart disease after cardioverter defibrillator implantation

Anders Englund, MD, PhD^* , Steffen Behrens, MD, Karl Wegscheider, PhD, Edward Rowland, MD, FESC, FACC^* for the European 7219 Jewel Investigators

^* Department of Cardiological Sciences, St. George’s Hospital, London, UK
Department of Cardiology Uppsala University Hospital, Uppsala, Sweden
Medizinische Klinik II, Kardiologie and Pulmonologie, Klinikum Benjamin Franklin, Free University, Berlin, Germany
Department of Statistics and Economics, University of Hamburg, Hamburg, Germany

View larger version (45K): [in a new window]   Figure 1 Circadian distribution of the mean weighted frequencies of arrhythmic episodes for 310 patients. The bold line is the least square fit of a third-order harmonic. (A) Patients with nonischemic heart disease. (B) Patients with ischemic heart disease.

View larger version (47K): [in a new window]   Figure 2 Circadian distribution of the mean weighted frequencies of arrhythmia storms for 109 patients. The bold line is the least square fit of a third-order harmonic. (A) Patients with nonischemic heart disease. (B) Patients with ischemic heart disease.