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Myocardial contractile reserve on dobutamine echocardiography predicts late spontaneous improvement in cardiac function in patients with recent onset idiopathic dilated cardiomyopathy

^a Cardiac Noninvasive Laboratory, Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, USA

View larger version (17K): [in a new window]   Figure 1 Changes in LV WMSI, ESD, mitral inflow E-wave, LV mass (g/ml) and SIED in patients whose follow-up LVEF was >40% (group 1, solid black bars) versus patients whose follow-up LVEF was <40% (group 2, white bars) are shown. * = p < 0.05 versus group 1. EF = ejection fraction; ESD = end-systolic diameter; LV = left ventricular; SIED = end-diastolic sphericity index; WMSI = wall motion score index.

View larger version (28K): [in a new window]   Figure 2 Left ventricular ejection fraction at baseline, in response to dobutamine and on follow-up in patients with LVEF >40% (left panel) and with LVEF <40% (right panel) on follow-up. Horizontal bars indicate the mean value of LVEF in each group. LVEF = left ventricular ejection fraction.

View larger version (16K): [in a new window]   Figure 3 Linear regression analysis showing correlation between LVEF on dobutamine and LVEF on follow-up. LVEF = left ventricular ejection fraction. y = 10.8108 + 1.08*x; adjusted r2 = 0.68.