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Randomized comparison of coronary stent implantation and balloon angioplasty in the treatment of de novo coronary artery lesions (START)

A four-year follow-up

Amadeo Betriu, MD^*, Monica Masotti, MD^*, Antoni Serra, MD^*, Joaquin Alonso, MD, Francisco Fernández-Avilés, MD, Federico Gimeno, MD, Thierry Colman, MD, Javier Zueco, MD, Juan L. Delcan, MD, Eulogio García, MD and José Calabuig, MD^||

^* Hospital Clínic, Barcelona, Spain
Hospital Clínico Universitario, Valladolid, Spain
Hospital Universitario Marqués de Valdecilla, Santander, Spain
Hospital General Universitario Gregorio Marañón, Madrid, Spain
^|| Clínica Universitaria, Pamplona, Spain

View larger version (18K): [in a new window]   Figure 1 Cumulative frequency distribution curves for stent and angioplasty groups showing minimal luminal diameter at baseline, immediately postprocedure and at six-month follow-up. Preprocedural curves had a similar distribution of minimal luminal diameter among stent and angioplasty groups. At six months, both groups had reduced values, but a significant difference in diameter persisted in favor of the stent group.

View larger version (10K): [in a new window]   Figure 2 Kaplan-Meier survival curves for cardiac events (death, MI, coronary artery bypass surgery and repeat angioplasty) during the four-year follow-up period. The stent group showed significantly fewer events when compared with the angioplasty group.