This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hügel, S. Articles by Neubauer, S. Search for Related Content PubMed PubMed Citation Articles by Hügel, S. Articles by Neubauer, S.

Evidence against a role of physiological concentrations of estrogen in post-myocardial infarction remodeling

Stephanie Hügel, MD^*, Martin Reincke, MD^*, Hinrik Strömer, MD^*, Johannes Winning, MD^*, Michael Horn, PhD^*, Charlotte Dienesch^*, Patricia Mora^*, Harald H. H. W. Schmidt, MD, Bruno Allolio, MD^* and Stefan Neubauer, MD^*

^* Medizinische Universitätsklinik, Würzburg, Germany
Institut für Pharmakologie und Toxikologie, Universität Würzburg, Würzburg, Germany

View larger version (93K): [in a new window]   Figure 1 Representative M-mode tracings of the short-axis LV in a non-OVX + Sham (a), a non-OVX + MI (b), an OVX + MI (c) and an OVX + E2 + MI rat (d) eight weeks after left coronary artery ligation. There is increased LV cavity dimension, akinesis and thinning of anterior wall in all rats with MI.

View larger version (24K): [in a new window]   Figure 2 Left ventricular developed pressure-volume curves for all experimental groups; *p < 0.017 sham versus corresponding MI. A right and downward shift of the curve was observed for all MI groups. (Open circles) Non-OVX + Sham, (filled circles) non-OVX + MI, (open triangles) OVX + Sham, (filled triangles) OVX + MI, (open squares) OVX + E2 + Sham, (filled squares) OVX + E2 + MI.