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Angiotensin I–converting enzyme and plasminogen activator inhibitor-1 gene variants: risk of mortality and fatal cardiovascular disease in an elderly population-based cohort

Bastiaan T. Heijmans, MSc^* , Rudi G. J. Westendorp, MD, PhD , Dick L. Knook, PhD^* , Cornelis Kluft, PhD^* and P. Eline Slagboom, PhD^*

^* Gaubius Laboratory, TNO Prevention and Health, Leiden, The Netherlands
Section of Gerontology and Geriatrics, Department of General Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands

View larger version (20K): [in a new window]   Figure 1 Kaplan-Meier estimate of 10-year cumulative survival according to ACE genotype for subjects 85-years-old.

View larger version (19K): [in a new window]   Figure 2 Kaplan-Meier estimate of 10-year cumulative survival according to PAI-1 genotype for subjects 85 years old.