Changes in left ventricular filling and left atrial function six months after nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy
Sherif F. Nagueh, MD, FACCa,
Nasser M. Lakkis, MD, FACCa,
Katherine J. Middleton, RCTa,
Donna Killip, RNa,
William A. Zoghbi, MD, FACCa,
Miguel A. Quiñones, MD, FACCa and
William H. Spencer, III, MD, FACCa
a Cardiology Section, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
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Figure 1 Left atrial (LA) stroke volume (SV) in the control group, and in the HOCM group pre- and post-NSRT (comparing controls with HOCM patients pre-NSRT: p < 0.001, 95% confidence intervals for difference of means: 10–22; comparing controls with HOCM patients post-NSRT: p < 0.001, 95% confidence intervals: 4.1–14.4).
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Figure 2 Left atrial (LA) ejection force in the control group, and in the HOCM group pre- and post-NSRT (comparing controls with HOCM patients pre-NSRT: p < 0.001, 95% confidence intervals: 6.46–23.5; comparing controls with HOCM patients post-NSRT: p = 0.019, 95% confidence intervals: 1.3–13.6).
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Figure 3 Left atrial (LA) kinetic energy (KE) in the control group, and in the HOCM group pre- and post-NSRT (comparing controls with HOCM patients pre-NSRT: p < 0.001, 95% confidence intervals: 30–59.6; comparing controls with HOCM patients post-NSRT: p = 0.001, 95% confidence intervals: 9.3–36).
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Figure 8 Relation of changes in exercise duration to those in left ventricular passive filling volume.
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LA pre-A volume versus 
