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Sinus node function and ventricular repolarization during exercise stress test in long QT syndrome patients with KvLQT1 and HERG potassium channel defects

^a Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland

View larger version (19K): [in a new window]   Figure 1 The relationship between relative maximal sinus rate (percent achieved heart rate of the expected age-related heart rate) and QT interval (registered at heart rate 130 beats/min) during exercise.

View larger version (19K): [in a new window]   Figure 2 The behavior of QT interval in LQTS patients and controls during exercise (left panel) and recovery (right panel). *Statistically significant difference between controls and all patient groups, #between LQT1 pore region group and LQT2 group, +between LQT1 C-terminus group and LQT2 patients and @between LQT1 groups. One symbol stands for p value <0.05, two symbols for p < 0.01 and three symbols for p < 0.001.

View larger version (24K): [in a new window]   Figure 3 QT intervals at specified heart rates during exercise and recovery in LQTS patients and control subjects.