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J Am Coll Cardiol, 1999; 34:777-786
© 1999 by the American College of Cardiology Foundation
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Independent and incremental value of coronary artery calcium for predicting the extent of angiographic coronary artery disease

Comparison with cardiac risk factors and radionuclide perfusion imaging

Axel Schmermund, MD*, Ali E. Denktas, MD§, John A. Rumberger, PhD, MD, FACC*, Timothy F. Christian, MD, FACC*, Patrick F. Sheedy, II, MD{dagger}, Kent R. Bailey, PhD{ddagger} and Robert S. Schwartz, MD, FACC*

* Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota, USA
{dagger} Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, Minnesota, USA
{ddagger} Section of Biostatistics, Mayo Clinic and Foundation, Rochester, Minnesota; USA
§ University of Texas–Houston Medical School, Department of Internal Medicine (Cardiology Division), Houston, Texas, USA



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Figure 1 (A) Absolute number of patients in each category of CAGE ≥20 scores. (B) Absolute number of patients in each category of CAGE ≥50 scores.

 


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Figure 2 (A) Relation between CAGE ≥20 scores (Y-axis) and loge-transformed total calcium scores (X-axis). (B) Relation between CAGE ≥50 scores (Y-axis) and loge-transformed total calcium scores (X-axis).

 


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Figure 3 (A) Relation between CAGE ≥20 scores (Y-axis) and total calcium scores (X-axis) independent from either risk factors or radionuclide perfusion scores. The plot shows the residuals from regressing cardiac risk factors and radionuclide perfusion scores against CAGE ≥20 scores and residuals from regressing cardiac risk factors and radionuclide perfusion scores against total calcium scores. The scales are comparable with those in Figure 2, because unstandardized residuals were used. Negative values are a result of predictions with lower values than actual observations, and positive values are a result of predictions greater than actual observations. (B) Independent relation between CAGE ≥50 scores (Y-axis) and total calcium scores (X-axis). The residuals from regressing cardiac risk factors and radionuclide perfusion scores against CAGE ≥50 scores (Y-axis) and the residuals from regressing cardiac risk factors and radionuclide perfusion scores against total calcium scores are shown. The explanations provided for (A) also apply here.

 




 
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