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Factors correlating with risk of mortality after transmyocardial revascularization

Daniel Burkhoff, MD, PhD^*, Margaret N. Wesley, PhD, Jon R. Resar, MD, FACC and Allan M. Lansing, MD

^* Department of Medicine, Columbia University, New York, New York, USA
Information Management Services, Inc, Silver Spring, Maryland, USA
Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
Audubon Heart Center, Louisville, Kentucky, USA

View larger version (18K): [in a new window]   Figure 1 Kaplan-Meier curves depicting survival in patients having (overall anatomic myocardial perfusion index score [AMP] = 1) or not having (overall AMP = 0) unobstructed blood flow to a major vessel in at least one vascular territory. On the basis of univariate analysis, this factor was the strongest single factor which correlated with the risk of mortality after transmyocardial revascularization (TMR) (p = 0.002).

View larger version (17K): [in a new window]   Figure 2 Kaplan-Meier curves depicting survival in patients having (anterior AMP = 1) or not having (anterior AMP = 0) unobstructed blood flow to the left anterior descending artery. On the basis of univariate analysis, this factor also correlated with the risk of mortality after TMR (p = 0.005). Abbreviations as in Figure 1.

View larger version (17K): [in a new window]   Figure 3 Kaplan-Meier curves depicting survival in patients having had (coronary artery bypass graft [CABG] = 1) or not having had (CABG = 0) previous coronary bypass surgery. On the basis of univariate analysis, prior CABG predicted a better outcome after transmyocardial revascularization (TMR) (p = 0.003).

View larger version (18K): [in a new window]   Figure 4 Kaplan-Meier curves depicting survival in patients having (inferior AMP = 1) or not having (inferior AMP = 0) unobstructed blood flow to the posterior descending artery. On the basis of univariate analysis, this exhibited a statistically significant, though weak correlation with the risk of mortality after TMR (p = 0.05). Abbreviations as in Figure 1.