Clinical validation of intravascular ultrasound imaging for assessment of coronary stenosis severity
Comparison with stress myocardial perfusion imaging
Toshihiko Nishioka, MDa,
Aman M. Amanullah, MD*,
Huai Luo, MD*,
Hans Berglund, MD*,
Chong-Jin Kim, MD*,
Tomoo Nagai, MD*,
Naohiro Hakamata, MDa,
Shuichi Katsushika, MDa,
Akimi Uehata, MDa,
Bonpei Takase, MDa,
Kazushige Isojima, MDa,
Daniel S. Berman, MD, FACC* and
Robert J. Siegel, MD, FACC*
a Division of Cardiology, Self-Defense Forces Central Hospital, Setagaya-ku, Tokyo 154-8532, Japan
* Division of Cardiology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, California 90048, USA
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Figure 1 Top panel: Longitudinal view of a schematic presentation of the lumen areas and the EEL (external elastic lamina) areas at the proximal reference site, lesion site and distal reference site. Middle panel: IVUS images from the proximal reference site, lesion site and distal reference site of a patient with a significant coronary stenosis. Bottom panel: Cross-sectional view of a schematic presentation of the lumen areas, wall and EEL areas at the proximal reference site, lesion site and distal reference site.
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Figure 2 Scattergraph shows raw data of all lesion lumen areas correspondent to each mean reference EEL area. The dotted line (Y = 4.0) and the solid line (Y = 0.1X + 2.6) indicate the cutoff line that discriminates the SPECT (+) group from the SPECT (–) group. EEL, external elastic lamina; SPECT, single-photon emission computed tomography. Open circle = SPECT (+); solid circle = SPECT (–).
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Figure 3 Scattergraph shows raw data of all lesion percent area stenoses correspondent to each EEL area ratio. The dotted line and solid line (Y = 0.23X + 47.0) indicate the cutoff value and line, respectively, which discriminates the SPECT (+) group from the SPECT (–) group. EEL, external elastic lamina; SPECT, single-photon emission computed tomography. Open circle = SPECT (+); solid circle = SPECT (–).
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Figure 4 Scattergraph shows raw data of all luminal percent area stenoses correspondent to each mean reference percent area stenosis. The dotted line and solid line (Y = –0.21X + 68.0) indicate the cutoff value and line that discriminates the SPECT (+) group from the SPECT (–) group. SPECT, single-photon emission computed tomography. Open circle = SPECT (+); solid circle = SPECT (–).
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Figure 5 Scattergraph shows raw data of all corrected percent area stenoses correspondent to each mean reference percent area stenosis. The dotted line and solid line (Y = 0.24X + 66.0) indicate the cutoff value and line, which discriminates the SPECT (+) group from the SPECT (–) group. SPECT, single-photon emission computed tomography. Open circle = SPECT (+); solid circle = SPECT (–).
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