Losartan improves exercise tolerance in patients with diastolic dysfunction and a hypertensive response to exercise
James G. Warner, Jr., MD, EdD, FACCa,
D. Christopher Metzger, MDa,
Dalane W. Kitzman, MD, FACCa,
Deborah J. Wesley, RN, BSNa and
William C. Little, MD, FACCa
a Cardiology Section, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1045, USA
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Figure 1 Plot of exercise duration (A) and peak systolic blood pressure (BP) (B) during baseline and during treatment with placebo and losartan. Treatment with losartan increased exercise time and reduced peak systolic BP during exercise compared to baseline and placebo.
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