Blood flow–metabolism imaging with positron emission tomography in patients with diabetes mellitus for the assessment of reversible left ventricular contractile dysfunction 1
Heiko Schöder, MDa,b,
Roxana Campisi, MDa,b,
Tohru Ohtake, MDa,b,
Carl K. Hoh, MDa,b,
Dae H. Moon, MDa,b,
Johannes Czernin, MDa,b and
Heinrich R. Schelbert, MDa,b
a Department of Molecular and Medical Pharmacology, Division of Nuclear Medicine, UCLA School of Medicine, Los Angeles, California, USA
b Laboratory of Structural Biology and Molecular Medicine, University of California, Los Angeles, California, USA
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Figure 1 Plasma glucose concentrations in group I diabetic patients and group II nondiabetic patients at baseline (open bars) and after intravenous insulin injection (group I) or oral glucose load (group II), respectively (shaded bars). Data are mean ± 1 SD.
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Figure 2 Representation of coronary vascular territories according to their positron emission tomography blood flow–metabolism imaging patterns and changes in regional wall motion (WM) after coronary revascularization.
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Figure 3 Changes in regional wall motion after coronary revascularization in group I diabetic patients (Top) and group II nondiabetic patients (Bottom) according to their positron emission tomography blood flow–metabolism imaging patterns.
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Figure 4 Improvement in global left ventricular function after coronary revascularization and its relationship to the number of positron emission tomography mismatch territories; open bars indicate presurgical, shaded bars postsurgical left ventricular ejection fraction. Data are mean ± 1 SD.
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