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Assessment of regional and global left ventricular function by reinjection Tl-201 and rest Tc-99m sestamibi ECG-gated SPECT

Comparison with three-dimensional magnetic resonance imaging

Eiji Tadamura, MD^a, Takashi Kudoh, MD^a* , Makoto Motooka, MD^*, Masayuki Inubushi, MD^a* , Seiji Shirakawa, RT^a* , Naoya Hattori, MD^a* , Tomohisa Okada, MD^a* , Tetsuya Matsuda, MD^a, Takaaki Koshiji, MD, Kazunobu Nishimura, MD, Katsuhiko Matsuda, MD and Junji Konishi, MD^a*

^a Department of Nuclear Medicine and Diagnostic Imaging, Kyoto University Graduate School of Medicine, Kyoto, Japan
^* Third Division, Department of Internal Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
Department of Medical Informatics, Kyoto University Graduate School of Medicine, Kyoto, Japan
Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

View larger version (74K): [in a new window]   Figure 1 A typical LV end-diastolic (left) and end-systolic (right) short axis images of reinjection-g-SPECT (top), MIBI-g-SPECT (middle) and MRI (bottom) in a patient with old myocardial infarction. Regional wall motion and thickening were impaired in anteroseptal and inferolateral regions.

View larger version (17K): [in a new window]   Figure 2 Scatter plots are shown for EDV obtained with reinjection-g-SPECT (filled circle) (y = 5.7 + 0.91x; r = 0.85; SEE = 18.7 ml) and MIBI-g-SPECT (open circle) (y = 3.8 + 0.92x; r = 0.92; SEE = 13.1 ml).

View larger version (19K): [in a new window]   Figure 3 Scatter plots are shown for ESV obtained with reinjection-g-SPECT (filled circle) (y = 0.30 + 1.03x; r = 0.94; SEE = 10.3 ml) and MIBI-g-SPECT (open circle) (y = 1.28 + 0.98x; r = 0.97; SEE = 6.7 ml).

View larger version (20K): [in a new window]   Figure 4 Scatter plots are shown for LVEF obtained with reinjection-g-SPECT (filled circle) (y = –6.77 + 1.06x; r = 0.92; SEE = 5.9%) and MIBI-g-SPECT (open circle) (y = 0.34 + 0.93x; r = 0.94; SEE = 4.4%).