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Effect of intensive therapy for heart failure on the vasodilator response to exercise

^a Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA

View larger version (31K): [in a new window]   Figure 1 Calf blood flow at rest and peak flow after 2 min of isotonic exercise at 30 cycles/min (Ex30) and 60 cycles/min (Ex60) in control subjects and heart-failure patients before (Pre-rx) and after (Post-rx) medical therapy. *p 0.05 compared to Pre-rx.

View larger version (30K): [in a new window]   Figure 2 Calf hyperemic volume in the 4 min following isotonic exercise at 30 cycles/min (Ex30) and 60 cycles/min (Ex60) in control subjects and heart-failure patients before (Pre-rx) and after (Post-rx) medical therapy. *p 0.05 compared to Pre-rx.

View larger version (23K): [in a new window]   Figure 3 Peak calf blood flow (left) after five min of arterial occlusion in control subjects (Control), decompensated heart-failure patients (Pre-rx), and the same patients after intensive medical therapy (Post-rx). Total hyperemic volume (right) is shown in the four min following arterial occlusion in the same subject groups. *p 0.05 compared to Pre-rx.