Integrated evaluation of relation between coronary lesion features and stress echocardiography results: the importance of coronary lesion morphology
Branko D. Beleslin, MDa,
Miodrag Ostojic, MD, PhD, FESC, FACCa,
Ana Djordjevic-Dikic, MDa,
Rade Babic, MDa,
Milan Nedeljkovic, MDa,
Goran Stankovic, MDa,
Sinisa Stojkovic, MDa,
Jelena Marinkovic, PhDa,
Ivana Nedeljkovic, MDa,
Jelena Stepanovic, MDa,
Jovica Saponjski, MDa,
Zorica Petrasinovic, MDa,
Srecko Nedeljkovic, MD, PhD, FESC, FACCa and
Vladimir Kanjuh, MD, PhDa
a University Institute for Cardiovascular Diseases, Clinical Center of Serbia, Department for Diagnostic and Catheterization Labs., 8 Koste Todorovica, 11000 Belgrade, Yugoslavia
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Figure 1 Bar graph showing the distribution of coronary stenosis and plaque morphology types in 153 patients. Striped columns = simple; dotted columns = complex.
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Figure 2 Relation between the sensitivity (solid triangles), specificity (asterisks) and diagnostic accuracy (solid squares) of the exercise (A), dobutamine (B), and dipyridamole (C) stress echocardiography as a function of quantitatively assessed percent diameter stenosis (n = 153). The best angiographic cutoff value with 95% confidence intervals (CI) for each stress echocardiography test is presented.
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Figure 3 Bar graph showing the sensitivity of exercise (Ex), dobutamine (Dob) and dipyridamole (Dip) in the patients with simple and complex lesion morphology. Sensitivity of dipyridamole and dobutamine was significantly higher (p < 0.01) in the group of patients with complex lesion morphology. There was a significant difference between all three stress echocardiography tests (p < 0.05) for simple lesion types while for complex lesions the difference was statistically significant (p = 0.014) only between exercise and dipyridamole.
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