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Limited myocardial contractile reserve and chronotropic incompetence in patients with chronic Chagas’ disease

Assessment by dobutamine stress echocardiography

^a Centro de Investigaciones J.F. Torrealba, Hospital Universitario de Caracas, Centro Médico de Caracas, Caracas, Venezuela
^b Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA

View larger version (18K): [in a new window]   Figure 1 Mean HR (± SD) responses to stepwise dobutamine infusion in the control group, and in Chagas’ group 1 (abnormal serologic results only with normal wall motion at baseline) and 2 (baseline wall motion abnormalities) patients. For definition of groups see "Methods" section.

View larger version (16K): [in a new window]   Figure 2 (A) Left ventricular end-diastolic areas at baseline and at peak dobutamine infusion. (B) Left ventricular end-systolic area at baseline and at peak dobutamine infusion. (C) Left ventricular fractional area change (percent) at baseline and at peak dobutamine infusion.