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Suppression of sustained ventricular tachyarrhythmias: a comparison of d,l-sotalol with no antiarrhythmic drug treatment

^a Eberhard-Karls-University, Medical Department III, Tübingen, Germany

View larger version (17K): [in a new window]   Figure 1 Life-table curves for recurrence of ventricular tachycardia or ventricular fibrillation in the three study groups. Recurrences were significantly more frequent in patients of the ICD-only group in comparison to the Sotalol group (p = 0.0008) and the ICD/sotalol group (p = 0.023). There was no significant difference between the sotalol group and the ICD/sotalol group (p = 0.288). Two patients in the sotalol group and one patient in the ICD group died suddenly and in all three patients this was the first recurrence of ventricular tachyarrhythmias (see methods for the definition of a recurrence of ventricular tachycardia or ventricular fibrillation).

View larger version (14K): [in a new window]   Figure 2 Total mortality was not different between the three study groups (sotalol group versus ICD group p = 0.623, sotalol group versus ICD/sotalol group p = 0.9, ICD group versus ICD/sotalol group p = 0.63). In the sotalol group and the ICD/sotalol group two patients died suddenly respectively, in the ICD group one patient died suddenly. Minimum value on the y-axis is 50%! (see methods for the definition of sudden death, cardiac death and noncardiac death).