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J Am Coll Cardiol, 1999; 33:267-272
© 1999 by the American College of Cardiology Foundation
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Effect of congestive heart failure on in vivo canine aortic elastic properties

Zia Khan, MD*, Ronald W. Millard, PhD{dagger}, Marjorie Gabel*, Richard A. Walsh, MD, FACC* and Brian D. Hoit, MD, FACC*

* Division of Cardiology, Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio, USA
{dagger} Department of Pharmacology and Cell Biophysics, University of Cincinnati, Cincinnati, Ohio, USA



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Figure 1 Representative pressure–dimension curves before (top) and after (bottom) pacing-induced heart failure in the baseline state (squares) and after nitroprusside (circles) and dobutamine (triangles). A shift of the pressure–dimension relation with nitroprusside and dobutamine occurred only after heart failure was produced.

 


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Figure 2 Stress–strain curves before (top) and after (bottom) pacing-induced heart failure in the baseline state (squares) and after nitroprusside (circles) and dobutamine (triangles). Stress–strain relations were similar in both states.

 




 
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