Left atrial filling volume can be used to reliably estimate the regurgitant volume in mitral regurgitation
Andrea Rossi, MDa,
Giorgio Golia, MDa,
Giampaolo Gasparini, MDa,
Maria Antonia Prioli, MDa,
Maurizio Anselmi, MDa and
Piero Zardini, MDa
a Division of Cardiology, University of Verona, Verona, Italy

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Figure 1 A representative example showing how left atrial boundaries were traced in apical four-chamber view (upper panel) and two-chamber view (middle panel) during end-systole (LAmax) and end-diastole (LAmin). A pulmonary vein velocity tracing (lower panel) shows how systolic (S) and diastolic (D) velocity were measured.
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Figure 2 Scatterplot of regurgitant volume measured by Doppler (Dpl-RVol) versus pulmonary vein systolic time-velocity integral compared to total pulmonary vein time-velocity integral (Pvs%) (A) and left atrial volume variation during ventricular systole (LAfill) (B) in study-group patients.
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Figure 3 Correlation between regurgitant volume measured by Doppler (Dpl-RVol) and the regurgitant volume estimated by the regression equation in 54 patients of the prospective group. Dotted line represents the line of identity.
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Figure 4 Scatterplot of the difference between measured and estimated regurgitant volume on the y-axis and the mean of the two on the x-axis. This scatterplot shows clearly a significant underestimation of the regurgitant volume in patients with very large regurgitation (regurgitant volume higher than 80 ml) (see text for details).
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