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Effects of early captopril administration after thrombolysis on regional wall motion in relation to infarct artery blood flow

^a Department of Cardiology, Green Lane Hospital, Auckland, New Zealand

View larger version (33K): [in a new window]   Figure 1 Flow diagram.

View larger version (11K): [in a new window]   Figure 2 Cardiac mortality according to treatment randomization. Log-rank comparisons of cardiac mortality in the captopril (243) and placebo (250) groups at 1, 3 and 5 years were p = 0.044, p = 0.045 and p = 0.063, respectively. At these follow-up times the number of patients were 435, 332 and 122, respectively.

View larger version (19K): [in a new window]   Figure 3 Effect of captopril on regional wall motion in anterior infarction according to corrected TIMI frame counts. (A) Number of abnormal chords; (B) number of chords >2 SD below normal; (C) total hypokinetic chords. Only the comparisons indicated were significant.