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Improvement of exercise capacity by sarpogrelate as a result of augmented collateral circulation in patients with effort angina

Terumitsu Tanaka, MD^*, Masatoshi Fujita, MD, FACC, Izuru Nakae, MD^*, Shun-Ichi Tamaki, MD^*, Koji Hasegawa, MD, Yasuki Kihara, MD, Ryuji Nohara, MD and Shigetake Sasayama, MD, FACC

^* Division of Cardiology, Takeda Hospital, Kyoto University, Graduate School of Medicine, Kyoto, Japan
College of Medical Technology, Kyoto University, Kyoto, Japan
Department of Cardiovascular Medicine, Kyoto University, Graduate School of Medicine, Kyoto, Japan

View larger version (24K): [in a new window]   Figure 1 Individual changes in the exercise time up to until 0.1 mV ST depression after sarpogrelate pretreatment in groups A (patients with severely stenosed ischemia-related coronary artery) and B (patients with well-developed collateral circulation).

View larger version (19K): [in a new window]   Figure 2 Individual changes in the double product at 0.1 mV ST depression after sarpogrelate pretreatment in groups A (patients with severely stenosed ischemia-related coronary artery) and B (patients with well-developed collateral circulation).

View larger version (21K): [in a new window]   Figure 3 Individual changes in the severity score of the exercise myocardial perfusion scintigrams after sarpogrelate pretreatment in groups A (patients with severely stenosed ischemia-related coronary artery) and B (patients with well-developed collateral circulation).