JACC
HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
QUICK SEARCH:   [advanced]


     

J Am Coll Cardiol, 1998; 32:1672-1679
© 1998 by the American College of Cardiology Foundation
This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Motoyama, T.
Right arrow Articles by Yasue, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Motoyama, T.
Right arrow Articles by Yasue, H.

Vitamin E administration improves impairment of endothelium-dependent vasodilation in patients with coronary spastic angina

Takeshi Motoyama, MDa, Hiroaki Kawano, MDa, Kiyotaka Kugiyama, MDa, Osamu Hirashima, MDa, Masamichi Ohgushi, MDa, Ryusuke Tsunoda, MDa, Yasushi Moriyama, MDa, Yuji Miyao, MDa, Michihiro Yoshimura, MDa, Hisao Ogawa, MDa and Hirofumi Yasue, MDa

a Division of Cardiology, Kumamoto University School of Medicine, Kumamoto, Japan



View larger version (17K):

[in a new window]
  		Figure 1 Diagram of the study.

 


View larger version (12K):

[in a new window]
  		Figure 2 (A) Bar graphs showing the percent increase in brachial arterial diameter during reactive hyperemia before treatment in patients with coronary spastic angina (CSA) (solid bar) and controls (open bar). (B) Bar graphs showing the plasma {alpha}-tocopherol levels before treatment in patients with CSA (solid bar) and controls (open bar). (C) Bar graphs showing the plasma TBARS levels before treatment in patients with CSA (solid bar) and controls (open bar).

 


View larger version (16K):

[in a new window]
  		Figure 3 Percent increase in brachial arterial diameter during reactive hyperemia in patients with coronary spastic angina before and after treatment in the placebo group and the vitamin E group. *Significant effect of vitamin E treatment compared with values in placebo group, p < .001 by ANOVA. {ominus}, diltiazem + placebo; •, diltiazem + vitamin E.

 


View larger version (15K):

[in a new window]
  		Figure 4 Plasma {alpha}-tocopherol levels in patients with coronary spastic angina before and after treatment in the placebo group and the vitamin E group. *Significant effect of vitamin E treatment compared with values in placebo group, p < .001 by ANOVA. {ominus}, diltiazem + placebo; •, diltiazem + vitamin E.

 


View larger version (15K):

[in a new window]
  		Figure 5 Plasma TBARS levels in patients with coronary spastic angina before and after treatment in the placebo group and the vitamin E group. *Significant effect of vitamin E treatment compared with values in the placebo group, p < .001 by ANOVA. {ominus}, diltiazem + placebo; •, diltiazem + vitamin E.

 


View larger version (20K):

[in a new window]
  		Figure 6 Correlation between the percent increases in brachial arterial diameter during reactive hyperemia versus the changes of coronary arterial diameter in response to acetylcholine at a dose of 50 µg/min in patients with coronary spastic angina (squares) and controls (circles).

 




HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
Copyright © 1998 by the American College of Cardiology Foundation.