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J Am Coll Cardiol, 1998; 32:1207-1213
© 1998 by the American College of Cardiology Foundation
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Impairment of the nitric oxide–mediated vasodilator response to mental stress in hypertensive but not in hypercholesterolemic patients

Carmine Cardillo, MDa, Crescence M. Kilcoyne, RN, MSa, Richard O. Cannon, III, MDa and Julio A. Panza, MDa

a Cardiology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA



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Figure 1 Bars show the percent changes in forearm blood flow from baseline in response to mental stress in normotensive, hypertensive and hypercholesterolemic subjects. Values represent mean ± SEM.

 


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Figure 2 Bars show the effect of nitric oxide synthesis inhibition by NG-monomethyl-L-arginine (L-NMMA, 4 µmol/min) on the percent changes in forearm blood flow from baseline in normotensive, hypertensive and hypercholesterolemic subjects. Values represent mean ± SEM. Open box = saline; solid box = L-NMMA.

 


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Figure 3 Bars show the percent changes in forearm blood flow from baseline in response to intraarterial infusion of acetylcholine (30 µg/min) and sodium nitroprusside (3.2 µg/min) in normotensive (NV), hypertensive (HT) and hypercholesterolemic (HC) subjects. Values represent mean ± SEM.

 





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