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J Am Coll Cardiol, 1998; 32:927-935
© 1998 by the American College of Cardiology Foundation
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Attenuation-corrected 99mTc-tetrofosmin single-photon emission computed tomography in the detection of viable myocardium: comparison with positron emission tomography using 18F-fluorodeoxyglucose

Ichiro Matsunari, MD*, Guido Böning*, Sibylle I. Ziegler, PhD*, Stephan G. Nekolla, PhD*, Jens C. Stollfuss, MD*, Istvan Kosa, MD*, Edward P. Ficaro, PhD{dagger} and Markus Schwaiger, MD, FACC*

* Nuklearmedizinische Klinik und Poliklinik der Technischen Universität München, Klinikum rechts der Isar, Munich, Germany
{dagger} Department of Internal Medicine, Division of Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA



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Figure 1 An 82-year-old man with three-vessel coronary artery disease. (A) The non–attenuation-corrected 99mTc-tetrofosmin images (left), attenuation-corrected 99mTc-tetrofosmin images (center) and positron emission tomography with 18F-fluorodeoxyglucose (right). (B) Reconstructed transmission images of the patient.

 


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Figure 2 Bar charts showing the percentage of concordant segments regarding viability between 99mTc-tetrofosmin SPECT and FDG PET (labeled as Concordance), the percentage of 99mTc-tetrofosmin defect segments (<50% of peak activity) within viable segments by FDG PET (labeled as TDV) and the percentage of 99mTc-tetrofosmin uptake segments (≥50% of peak) within nonviable segments (labeled as TUNV) from all 216 segments. Data using a 50% threshold cutoff to define viability by FDG PET are illustrated on the left, and those using a 60% threshold cutoff are on the right. Values are calculated on the patient basis and are expressed as mean ± SD. NC = non–attenuation-corrected image; AC = attenuation-corrected image; n = the number of patients who were eligible for the analysis.

 


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Figure 3 Bar charts showing the percentage of concordant segments regarding viability between 99mTc-tetrofosmin SPECT and FDG PET (labeled as Concordance), the percentage of 99mTc-tetrofosmin defect segments (<50% of peak activity) within viable segments by FDG PET (labeled as TDV) and the percentage of 99mTc-tetrofosmin uptake segments (≥50% of peak) within nonviable segments (labeled as TUNV) from 166 asynergic segments. Data using a 50% threshold cutoff to define viability by FDG PET are illustrated on the left, and those using a 60% threshold cutoff are on the right. Values are calculated on the patient basis, and are expressed as mean ± SD. NC = non–attenuation-corrected image; AC = attenuation corrected image; n = the number of patients who were eligible for the analysis.

 


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Figure 4 Bar charts showing the percentage of concordant segments regarding viability between 99mTc-tetrofosmin SPECT and FDG PET (labeled as Concordance), the percentage of 99mTc-tetrofosmin defect segments (<50% of peak activity) within viable segments by FDG PET (labeled as TDV) and the percentage of 99mTc-tetrofosmin uptake segments (≥50% of peak) within nonviable segments (labeled as TUNV) in the anterior-lateral (A) and inferior-septal regions (B). Data using a 50% threshold cutoff to define viability by FDG PET are illustrated on the left, and those using a 60% threshold cutoff are on the right. Values are calculated on the patient basis, and are expressed as mean ± SD. NC = non–attenuation-corrected image; AC = attenuation corrected image; n = the number of patients who were eligible for the analysis.

 





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Copyright © 1998 by the American College of Cardiology Foundation.