Echocardiographic and biochemical evaluation of the development and progression of carcinoid heart disease
William D. Denney, MD*,
W. Evans Kemp, Jr., MD*,
Lowell B. Anthony, MD
,
John A. Oates, MD
and
Benjamin F. Byrd, III, MD, FACC*
* Division of Cardiology, Vanderbilt University, Nashville, Tennessee, USA
Department of Internal Medicine, Vanderbilt University, Nashville, Tennessee, USA
Division of Medical Oncology, Tulane University, New Orleans, Louisiana, USA

View larger version (37K):
[in a new window]
|
Figure 1 Scoring system for carcinoid valvular heart disease (CVHD% score). TR = tricuspid regurgitation, RA = right atrium, PV = pulmonic valve, m/s = meters/second, and PI = pulmonic insufficiency.
|
|

View larger version (71K):
[in a new window]
|
Figure 2 Time-integrated urinary 5-HIAA for one patient. Shaded area represents the integral value.
|
|

View larger version (21K):
[in a new window]
|
Figure 3 Comparison of urinary 5-HIAA levels in patients with stable (group A) and progressive (group B) carcinoid heart disease. Bars represent median values with ranges noted by hash marks.
|
|

View larger version (20K):
[in a new window]
|
Figure 4 Urinary 5-HIAA levels in patient without carcinoid heart disease at baseline who remained stable (group 1A) or developed carcinoid heart disease during follow-up (group 1B). Bars represent median values with ranges noted by hash marks.
|
|
Copyright © 1998 by the American College of Cardiology Foundation.