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Clinical predictors of early infarct-related artery patency following thrombolytic therapy: importance of body weight, smoking history, infarct-related artery and choice of thrombolytic regimen: the GUSTO-I experience

^a Cardiovascular Research Institute and the GUSTO-I Core Angiographic Laboratory, The George Washington University, Washington, DC, USA
^* Duke University, Durham, North Carolina, USA

View larger version (20K): [in a new window]   Figure 1 Logistic regression analysis. The probability of 90 min infarct-related artery TIMI 3 flow adjusted for body weight and infarct artery in patients who never smoked. = t-PA, right or circumflex coronary artery. = t-PA, left anterior descending coronary artery. = streptokinase regimen, right or circumflex coronary artery. = streptokinase regimen, left anterior descending coronary artery.

View larger version (20K): [in a new window]   Figure 2 Multivariable analysis: adjusted odds ratios with 95% confidence limits for infarct related artery TIMI 3 flow 90 min postthrombolytic therapy according to treatment regimen, infarct related artery and body weight. The 95% confidence limits for any given weight difference displayed are small and contained within the diamond representation. A ratio >1.0 denotes greater likelihood TIMI 3 flow relative to TIMI 0,1 or 2 flow. SK = streptokinase. IRA = infarct-related artery. RCA/Lcx = right coronary artery and left circumflex coronary artery. LAD = Left anterior descending coronary artery.