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Endothelial cell damage and angiotensin-converting enzyme insertion/deletion genotype in elderly hypertensive patients

Kazuomi Kario, MD, PhD^*, Takefumi Matsuo, MD, PhD, Hiroko Kobayashi, PhD, Nobuyuki Kanai, MD, PhD, Satoshi Hoshide, MD^*, Takeshi Mitsuhashi, MD, PhD^*, Uichi Ikeda, MD, PhD^*, Shinichi Nishiuma, MD^||, Masafumi Matsuo, MD, PhD^|| and Kazuyuki Shimada, MD, PhD^*

^* Department of Cardiology, Jichi Medical School, Tochigi, Japan
Department of Pathology, Jichi Medical School, Tochigi, Japan
Department of Internal Medicine, Hyogo Prefectural Awaji Hospital, Hyogo, Japan
Central Laboratory, Hyogo Prefectural Awaji Hospital, Hyogo, Japan
^|| Division of Genetics, International Center for Medical Research, Kobe University School of Medicine, Kobe, Japan

View larger version (32K): [in a new window]   Figure 1 Relationship between BP and the levels of endothelial cell-derived markers in hypertensive patients with ACE II genotype (left) and with ACE DD genotype (right).