Effects of afterload reduction on vena contracta width in mitral regurgitation
Ali M. Kizilbash, MDa,
DuWayne L. Willett, MD, FACCa,
M. Elizabeth Brickner, MD, FACCa,
Sheila K. Heinle, MD, FACCa and
Paul A. Grayburn, MD, FACCa
a Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center and Department of Veterans Affairs Medical Center, Dallas, Texas, USA

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Figure 1 Individual values for VCW at baseline and after sodium nitroprusside. Despite the absence of a significant change in mean values, individual patients had marked directional variability.
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Figure 2 Change in VCW from baseline to after nitroprusside for the 31 patients in the study. Closed circles represent patients thought to have a dynamic orifice according to cause of MR; open circles represent patients thought to have a fixed orifice according to cause of MR.
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Figure 3 Color flow images from a patient in this study. Left, Baseline image with a VCW of 0.4 cm (arrows). The RgV was 35 ml and EROA was 0.4 cm2). Right, During sodium nitroprusside infusion, VCW increased to 0.6 cm (arrows). The RgV and EROA increased to 61 ml and 0.6 cm2, respectively.
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